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Marijuana Use and Pregnancy; Research Review

May 28, 20104 CommentsRisks of Cannabis , ,

I recently had a 28 year old pregnant patient ask me about the potential effects of cannabis use on her pregnancy.  She had been using cannabis to treat ongoing migraine headaches with great results.    Because I very rarely work with pregnant women as part of my professional practice I had to hit the books and look for what research is out there on how cannabis affects the pregnancy, neonatal growth and the future development of the child.   Here is a summary of what I found.

In 1992, self reported cannabis use during pregnancy was 2.9% of pregnant women.  However some studies found use to be between 10-16% in middle class samples and 23-30% in inner-city populations.

The major study that I found was the Ottawa Prenatal Prospective Study (OPPS) which looked at cannabis use in 682 women in Ottawa Canada.

Studies during pregnancy are obviously limited by the small amount of people but this is what they found thus far (keep in my we often in medicine think medications are safe only to find out that they are in fact dangerous)

Cannabis’ impact on the overall course of pregnancy:

- reduction in gestational age by 1 week; increase in the frequency of contractions. Possible association with pre-term delivery. No physical abnormalities were found at birth.  Heavy use was associated with ocular hypertention and severe epicanthus.

-low protein diets made the adverse effects of cannabis more pronounced.

Cannabis’ impact on growth and neonatal and infant behavior:

-infants have shown to have smaller head circumference.   Visual habituation is affected.   Prolonged startle response and resting tremors similar to patients undergoing opioid withdrawal.

Cannabis’ impact on adolescents:

-decrease in the ability to accomplish goal oriented tasks.

Based on the clinical research that has been completed I would strongly advise against medicating with cannabis during pregnancy.

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4 comments to “Marijuana Use and Pregnancy; Research Review”

  1. Kim | June 11, 2010 | Permalink Reply

    Hi. Just learned I am pregnant. I read your post, but am also looking into the research of Melanie Dreher in Jamaica. Her research indicates that there is no negative effect and perhaps even a positive one. She’s dean of Nursing at University of Iowa. Anyways, have you looked at her work, and what is your opinion after reading that. She has criticisms of the studies done in the U.S. for methodological reasons that couldn’t separate possible other causes.

    • admin | June 16, 2010 | Permalink Reply

      Kim- I will certainly look into her work… however i still think it is prudent not to put any drugs into your system when pregnant and err on the side of caution.

  2. Staceu | May 11, 2011 | Permalink Reply

    What did you suggest to your patient to deal with her migraine headacehes instead of marijuana?

    • admin | May 11, 2011 | Permalink Reply

      Honestly I referred her back to her OB/GYN to work with her on treating her headaches. Because of the medical malpractice potential, any non-ob/gyn, is going to refer to the women’s midwife or OB to treat her headaches. I wish I could give you more advice.

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